Ketcher 3.5.0

What’s Changed

New features

  • #6738 – Ability to change the number of monomers in a line

  • #5208 – Allow modifying amino acids on canvas

  • #6995 – Smart positioning of CIP stereo labels for atoms

  • #6852 – Improve the hydrophobicity graph in the “Calculate Properties” window

  • #6589 – API lacks support for 3 letter code sequence export in macro mode

  • #7070 – Include the removed versions of some 3D templates in the templates library in addition to the corrected ones

  • #7224 – Migrate to Indigo v1.33.0 in-browser module

Bugfixes and improvements

  • #7094 – Update the help document (3.4.)

  • #6294 – Hiding toolbar buttons doesn’t also hide disable the corresponding keyboard shortcut

  • #6930 – Replace File comparison (for MOL files ONLY!) operations with valid helper function - verifyFileExport

  • #7032 – Ketcher allows to make changes in sequence while being in nucleotide modification mode

  • #5971 – Inconsistent selection sensitivity when highlighting sequences

  • #7023 – Hydrophobicity section is missing tooltip icon and description

  • #6834 – Clicking on base card in RNA Builder does not scroll to selected base if multiple bases from the same section are selected

  • #7031 – Layout shift when entering symbol in sequence mode upon first macromolecules mode initialization

  • #6958 – Monomers positions are not preserved when pasting macromolecule in MOL format

  • #7200 – App crashes after modifying amino acids and switching to Micro mode

  • #7203 – N-methylation is shown as available for Hyp even though it shouldn’t be

  • #7142 – Monomer selection without bonds should work the same as with bonds

  • #7251 – Incorrect tooltips for properties and logic for the hydrophobicity graph in the “Calculate properties” window

  • #7130 – Incorrect calculation when part of a microstructure is selected - full structure is sent to Indigo

  • #7150 – Molecule mass should be calculated for partial selected micromolecule (ketcher part)

  • #7202 – Incorrect order of amino acid modification options in context menu

  • #7281 – App crashes when closing Ketcher

  • #6985 – Structure appears on incorrect canvas in molecules mode for several ketcher instances on same page

  • #7288 – Monomers shifts out of visible area when adjusting layout with ruler in sequence edit mode

  • #7318 – Bonds are overlapped by CIP labels when moving the structure or when the structure has small bond angles

Additional notes:

  • Ketcher 3.5.0 has been built and tested with Indigo version 1.33 (standalone and remote).