Ketcher 3.4.0¶
What’s Changed¶
New features¶
#6832 – Update the help document 3.3
#6625 – Support of expanded monomer option
#6271 – Support for CIP stereo labels in macromolecules mode
#5727 – Add “Calculate Properties” for macromolecules
#5797 – Highlighting attachment point of expanded monomers on hover in micromolecules mode
#7237 – Migrate to Indigo v1.32.0 in-browser module
Bugfixes and improvements¶
#4838 – Incorrect structure for Phe-L-Phenylalanine in template library
#5497 – Refactor (SnakeModePolymerBondRenderer): Create and use
SVGPathDAttributeUtil#6288 – Incorrect numbering in sequence
#6871 – Connection points become visible and broken if user switch window focus from one app to another and back
#6870 – Enter key adds undeletable preset to preset section
#4476 – Tooltips in sequence mode not disappear after right-click on letters
#6762 – System shows natural analog monomer as modified if source mol file contains only 3-letters natural analog name
#6791 – Change activation area of the New sequence button
#6788 – Reduce “Add new sequence” control width
#7008 – Support of expanded monomer options doesn’t work if monomer loaded from file/clipboard
#7007 – Rotation doesn’t work for expanded monomers on Molecules mode
#5791 – It is possible to expand unknown nucleotide on micromolecules canvas
#5789 – It is possible to expand ambiguous monomers on micromolecules canvas
#7014 – No tooltip displayed for the “Calculate Properties” button in main toolbar
#7019 – Data in “Calculate Properties” window disappears after switching browser tabs, selection remains
#7030 – Missing Celsius symbol (°C) in “Melting temperature” label
#7039 – App crashes when adding Ambiguous Amino Acids to peptide sequence with open Calculate Properties window
#7015 – Alt+C / Option+C hotkey does not open the “Calculate Properties” window
#7033 – calculateMacroProperties API is called immediately on sequence selection, even when Calculate Properties window is closed
#7018 – Unable to clear monomer selection after switching browser tabs
#7026 – Calculate properties for peptides are missing in case of mixed peptide and RNA/DNA chain
#7017 – “Calculate Properties” shows wrong behavior when sequence is connected to microstructure
#7062 – Rotation is incorrect upon exporting transformed monomer to SVG or PNG
#7074 – Formula in “Calculate Properties” window is not updated when selecting monomers with connected microstructure
#7034 – Unipositive ions default value is shown in nM instead of mM for double-stranded sequence selection
#7085 – Ketcher does not send bond type to Indigo if connection is different from R2–R1, causing missing data in “Calculate Properties”
#7027 – Incorrect highlight (missing fill) for leaving-group atoms
#7028 – Turquoise monomer outline has incorrect gap for attachment points and blue outline too thin
#7096 – Clearing canvas while “Calculate Properties” window is open causes console errors
#6974 – System removes monomers from Molecules mode canvas is switched from Macro mode (bonds remain!) if ketcher in embedded mode (custom style iframe)
#7118 – Cannot edit concentration values of unipositive ions and oligonucleotides in Calculate Properties
#7249 – Input fields for ion concentration and oligonucleotides become inactive after clearing or entering zero
#7266 – Oligonucleotides input field becomes unresponsive after entering zero
Additional notes:¶
Ketcher 3.4.0 has been built and tested with Indigo version 1.32 (standalone and remote).